Benzinga | Dec 21, 2021 04:06PM EST

Eiger BioPharmaceuticals Announces 1st Patient Enrolled In LIMT-2 Study

Eiger BioPharmaceuticals, Inc. (NASDAQ:EIGR), a commercial-stage biopharmaceutical company focused on the development of innovative therapies to treat and cure Hepatitis Delta Virus (HDV) and other serious rare diseases, today announced that the first patient has been enrolled in LIMT-2, a Phase 3 study of 48-week treatment with Peginterferon Lambda in patients with chronic hepatitis delta virus (HDV) infection. LIMT-2 will include 50 sites across 13 countries and a target enrollment of 150 patients.

"LIMT-2 is a single pivotal study to support approval of Peginterferon Lambda for the treatment of HDV," said David Cory, President and CEO of Eiger. "We believe that a well tolerated interferon will be preferred by physicians and HDV patients, leading to better compliance and improved outcomes. We now have two promising investigational treatments in Phase 3 for HDV, Lonafarnib and Peginterferon Lambda, which we expect will become foundational therapies to treat and cure HDV."

"There are now multiple late-stage, promising investigational treatments in development for HDV, each with a different mechanism of action and formulation for different routes of administration," said Pietro Lampertico, MD, PhD, LIMT-2 Principal Investigator, Professor of Gastroenterology, Director of the Gastroenterology and Hepatology Division, and Head of the "A. M. e A. Migliavacca" Center for Liver Disease at the Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, University of Milan, Italy. "It's an exciting time for both patients and physicians as we look toward the potential of multiple approved treatment options for the greater than 12 million HDV patients around the globe suffering from this severe disease."